OBJECTIVE:
The aim of this study was to evaluate the correlation between P-
wave indexes, echocardiographic
parameters, and CHA2DS2-VASc score in
patients without
atrial fibrillation and valvular
disease.
METHODS:
This retrospective
cross-sectional study included
patients of a
tertiary hospital with no
history of
atrial fibrillation,
atrial flutter, or valve
disease and collected data from June 2021 to May 2022. The exclusion criteria were as follows unavailable
medical records, pacemaker carriers, absence of echocardiogram
report, or uninterpretable
ECG. Clinical, electrocardiographic [i.e., P-
wave duration, amplitude, dispersion, variability, maximum, minimum, and P-
wave voltage in
lead I, Morris index, PR interval, P/PR ratio, and P-
wave peak
time], and echocardiographic data [i.e.,
left atrium and
left ventricle size,
left ventricle ejection fraction,
left ventricle mass, and
left ventricle indexed mass] from 272
patients were analyzed.
RESULTS:
PR interval (RHO=0.13, p=0.032),
left atrium (RHO=0.301, p<0.001) and
left ventricle diameter (RHO=0.197, p=0.001),
left ventricle mass (RHO=0.261, p<0.001), and
left ventricle indexed mass (RHO=0.340, p<0.001) were positively associated with CHA2DS2-VASc score, whereas P-
wave amplitude (RHO=-0.141, p=0.02), P-
wave voltage in
lead I (RHO=-0.191, p=0.002), and
left ventricle ejection fraction (RHO=-0.344, p<0.001) were negatively associated with the same score. The presence of the Morris index was associated with high CHA2DS2-VASc (p=0.022).
CONCLUSION:
Prolonged PR interval, Morris index, increased
left atrium diameter,
left ventricle diameter,
left ventricle mass, and
left ventricle indexed mass values as well as lower P-
wave amplitude, P-
wave voltage in
lead I, and
left ventricle ejection fraction values were correlated with higher CHA2DS2-VASc scores.
